Marc S Zumberg

Marc S Zumberg, M.D.

Professor

Department: MD-HEMATOLOGY/ONCOLOGY
Business Phone: (352) 273-7832

About Marc S Zumberg

Dr. Zumberg is recognized as an outstanding clinician-educator in the Division of Hematology/Oncology and the Department of Medicine.   He serves as Section Chief for benign hematology and holds various medical directorships.  He is chairman of the Shands Hospital Transfusion Committee.  He is noted as a key clinical faculty member in the Internal Medicine residency training program and the Division of Hematology/Oncology Fellowship Program.

Teaching Profile

Courses Taught
2017-2018,2020-2024
BMS6631 Hematology
2013-2018
MDT7200 Elect Top/Medicine
2016
MDC7200 Medicine Clerkship
2010-2013
MEL7948 Elect Top/Medicine
2024
BMS6816 Cancer Bio Clin Oncol

Board Certifications

  • Hematology
    American Board of Internal Medicine

Clinical Profile

Specialties
  • Cancer
  • Hematology
Areas of Interest
  • Anemia
  • Deep vein thrombosis
  • Hemochromatosis
  • Hereditary hemorrhagic telangiectasia
  • Immune thrombocytopenic purpura (ITP)
  • Sickle cell disease
  • Sickle cell test
  • Thrombocytopenia

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-9552-475X

Publications

2023
Consensus recommendations on peripheral blood smear review: defining curricular standards and fellow competency.
Blood advances. 7(13):3244-3252 [DOI] 10.1182/bloodadvances.2023009843. [PMID] 36930800.
2023
COVID-19 Associated Micro-Anastomotic Thrombosis After Abdominal Free Tissue Transfer: A Case Report and Literature Review.
Plastic surgery (Oakville, Ont.). 31(4):408-412 [DOI] 10.1177/22925503231161081. [PMID] 37908324.
2022
A Case of Acquired Hemophilia A and Congenital Hemophilia B.
Cureus. 14(10) [DOI] 10.7759/cureus.30324. [PMID] 36407152.
2022
A Rational Approach to Coagulation Testing.
Laboratory medicine. 53(4):349-359 [DOI] 10.1093/labmed/lmac005. [PMID] 35285898.
2022
Use of cell salvage and HBOC-201 in a pregnant Jehovah’s Witness with sickle beta+thalassaemia undergoing emergency caesarean section.
BMJ case reports. 15(11) [DOI] 10.1136/bcr-2022-251368. [PMID] 36396327.
2021
Clots in unusual places: lots of stress, limited data, critical decisions.
Hematology. American Society of Hematology. Education Program. 2021(1):92-99 [DOI] 10.1182/hematology.2021000237. [PMID] 34889361.
2021
Evidence-Based Minireview: Should warfarin or a direct oral anticoagulant be used in patients presenting with thrombosis in the splanchnic or cerebral veins?
Hematology. American Society of Hematology. Education Program. 2021(1):100-105 [DOI] 10.1182/hematology.2021000319. [PMID] 34889369.
2020
A case study of 10 patients administered HBOC‐201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option
Transfusion. 60(5):932-939 [DOI] 10.1111/trf.15778.
2020
Bleeding and Thrombotic Risk in Low Dose Heparin Infusion as Compared to Standard Dose Heparin Infusion.
Cureus. 12(5) [DOI] 10.7759/cureus.8339. [PMID] 32617214.
2020
Systems-based hematology: highlighting successes and next steps.
Blood advances. 4(18):4574-4583 [DOI] 10.1182/bloodadvances.2020002947. [PMID] 32960959.
2019
Anti-N and anti-Doa immunoglobulin G alloantibody-mediated delayed hemolytic transfusion reaction with hyperhemolysis in sickle cell disease treated with eculizumab and HBOC-201: case report and review of the literature.
Transfusion. 59(6):1907-1910 [DOI] 10.1111/trf.15198. [PMID] 30768787.
2017
A Patient-Centered Emergency Department Management Strategy for Sickle-Cell Disease Super-Utilizers.
The western journal of emergency medicine. 18(3):335-339 [DOI] 10.5811/westjem.2016.11.32273. [PMID] 28435481.
2017
Update in Hematology and Oncology: Evidence Published in 2016.
Annals of internal medicine. 166(7):W27-W32 [DOI] 10.7326/M17-0113. [PMID] 28358932.
2016
Management of granulomatous lymphocytic interstitial lung disease in a patient with common variable immune deficiency.
BMJ case reports. 2016 [DOI] 10.1136/bcr-2016-215624. [PMID] 27335365.
2016
Patient satisfaction with extended-interval warfarin monitoring.
Journal of thrombosis and thrombolysis. 42(4):486-93 [DOI] 10.1007/s11239-016-1385-9. [PMID] 27251646.
2015
Clinical experience with prophylactic fondaparinux in critically ill patients with moderate to severe renal impairment or renal failure requiring renal replacement therapy.
The Annals of pharmacotherapy. 49(3):270-7 [DOI] 10.1177/1060028014563325. [PMID] 25515864.
2015
Feasibility of Extended-interval Follow-up for Patients Receiving Warfarin.
Cardiovascular therapeutics. 33(3):98-103 [DOI] 10.1111/1755-5922.12115. [PMID] 25786578.
2015
Preclinical Medical Student Hematology/Oncology Education Environment.
Journal of cancer education : the official journal of the American Association for Cancer Education. 30(4):711-8 [DOI] 10.1007/s13187-014-0778-8. [PMID] 25637457.
2015
Reply: clinical experience with prophylactic fondaparinux in critically ill patients with moderate to severe renal impairment or renal failure requiring renal replacement therapy.
The Annals of pharmacotherapy. 49(5):614-5 [DOI] 10.1177/1060028015571658. [PMID] 25870447.
2015
Steps to diagnosis of a case of surreptitious intake of one of the newer direct oral anticoagulants: a case report and literature review.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 26(5):574-6 [DOI] 10.1097/MBC.0000000000000266. [PMID] 25692524.
2015
Successful implementation of a packed red blood cell and fresh frozen plasma transfusion protocol in the surgical intensive care unit.
PloS one. 10(5) [DOI] 10.1371/journal.pone.0126895. [PMID] 26010247.
2014
Hemophilia C in a Patient Undergoing Cardiac Surgery: Perioperative Considerations.
Seminars in cardiothoracic and vascular anesthesia. 18(3):297-301 [DOI] 10.1177/1089253214541295. [PMID] 25005855.
2014
Myelodysplastic syndrome and associated coagulopathy: a case report and review.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 25(2):172-5 [DOI] 10.1097/MBC.0b013e32836419a7. [PMID] 23867346.
2012
A case series of atypical presentations of thrombotic thrombocytopenic purpura.
Journal of clinical apheresis. 27(4):221-6 [DOI] 10.1002/jca.21216. [PMID] 22467376.
2012
Intentional low-molecular-weight heparin overdose: a case report and review.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 23(8):772-4 [DOI] 10.1097/MBC.0b013e328358e8af. [PMID] 23135382.
2012
Successful Implementation of a Packed Red Blood Cell and Fresh Frozen Plasma Transfusion Protocol in the Surgical Intensive Care Unit
Critical Care Medicine. 40
2011
Activated partial thromboplastin time versus antifactor Xa heparin assay in monitoring unfractionated heparin by continuous intravenous infusion.
The Annals of pharmacotherapy. 45(7-8):861-8 [DOI] 10.1345/aph.1Q161. [PMID] 21712506.
2011
Labor and delivery in a patient with hemophilia B.
International journal of obstetric anesthesia. 20(3):250-3 [DOI] 10.1016/j.ijoa.2011.04.003. [PMID] 21641201.
2010
A Massive Pulmonary Embolism Treatment Protocol: How Trauma Performance Improvement Affects Outcome Throughout the Hospital System
The American Surgeon. 76:145-148
2010
A massive pulmonary embolism treatment protocol: how trauma performance improvement affects outcome throughout the hospital system.
The American surgeon. 76(2):145-8 [PMID] 20336889.
2010
Sirolimus-induced severe hypertriglyceridemia in a lung transplant recipient.
Transplantation. 89(4):481-2 [DOI] 10.1097/TP.0b013e3181caa5e4. [PMID] 20177353.
2010
The use of anti-Xa assay to monitor intravenous unfractionated heparin therapy.
Journal of pharmacy practice. 23(3):210-6 [DOI] 10.1177/0897190010362172. [PMID] 21507816.
2009
Efficiency of a Weight-Based Low-Intensity Heparin Protocol for Patients Considered At High Risk for Bleeding
Critical Care Medicine. 37
2007
Acute liver failure occurring immediately following anti-D immune globulin infusion in a patient with chronic hepatitis B infection.
Digestive diseases and sciences. 52(4):914-9 [PMID] 17347887.
2007
Post-appendectomy thrombotic thrombocytopenic purpura: a case report and review of the literature.
American journal of hematology. 82(3):224-8 [PMID] 17034025.
2005
A feasibility study of continuing dose-reduced warfarin for invasive procedures in patients with high thromboembolic risk.
Chest. 127(3):922-7 [PMID] 15764777.
2005
Hydroxyurea therapy for sickle cell disease in community-based practices: a survey of Florida and North Carolina hematologists/oncologists.
American journal of hematology. 79(2):107-13 [PMID] 15929107.
2003
Role of phlebotomy in the management of hemoglobin SC disease: case report and review of the literature.
American journal of hematology. 73(2):121-5 [PMID] 12749014.
2002
A prospective randomized trial of prophylactic platelet transfusion and bleeding incidence in hematopoietic stem cell transplant recipients: 10,000/L versus 20,000/microL trigger.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 8(10):569-76 [PMID] 12434952.
2002
GM-CSF versus G-CSF: engraftment characteristics, resource utilization, and cost following autologous PBSC transplantation.
Cytotherapy. 4(6):531-8 [PMID] 12568989.
2001
Autoantibody formation in the alloimmunized red blood cell recipient: clinical and laboratory implications.
Archives of internal medicine. 161(2):285-90 [PMID] 11176745.
2001
Cesarean section combined with splenectomy in a parturient with immune thrombocytopenic purpura.
Journal of clinical anesthesia. 13(4):313-8 [PMID] 11435059.
2001
Successful use of argatroban as an anticoagulant in burn-related severe acquired antithrombin III deficiency after heparin failure.
Thrombosis and haemostasis. 86(6):1596-7 [PMID] 11776342.
2000
Management of a patient with a mechanical aortic valve and antibodies to both thrombin and factor V after repeat exposure to fibrin sealant.
American journal of hematology. 64(1):59-63 [PMID] 10815789.
1994
Inclusive education in Finland: present and future perspectives.
Psychological reports. 75(3 Pt 2):1519-22 [PMID] 7886174.

Grants

Dec 2023 ACTIVE
A Phase 2b, multicenter, randomized, double-blind study of safety and efficacy of TAK-755 (rADAMTS13) with minimal to no plasma exchange (PEX) in the treatment of immune-mediated thrombotic thrombocytopenic purpura (iTTP)
Role: Principal Investigator
Funding: IQVIA Holdings via TAKEDA DEVELOPMENT CENTER AMERICAS INC
Mar 2021 – Feb 2024
Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia – PATH
Role: Principal Investigator
Funding: CLEVELAND CLINIC FOU via NATL INST OF HLTH NHLBI
Mar 2021 – Feb 2023
Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia – PATH
Role: Principal Investigator
Funding: CLEVELAND CLINIC FOU via NATL INST OF HLTH NHLBI

Education

Fellowship
2000 · University of Florida College of Medicine
Residency
1997 · University of Florida College of Medicine
Medical Degree
1994 · University of Michigan

Contact Details

Phones:
Business:
(352) 273-7832
Emails:
Addresses:
Business Mailing:
PO Box 100278
GAINESVILLE FL 32610
Business Street:
PO Box 100278
GAINESVILLE FL 32610