Aaron J Franke

Aaron J Franke, M.D., M.S.

Assistant Professor

Business Phone: (352) 273-7832

About Aaron J Franke

Aaron Franke, MD, MS is an assistant professor of medicine in the Division of Hematology and Oncology at the University of Florida College of Medicine.

Dr. Franke received his undergraduate degree in psychology from Florida State University and his medical degree from Saba University School of Medicine in the Dutch Caribbean where he graduated summa cum laude.

He completed his internship and residency in Internal Medicine at University of Florida where he was recognized as the exemplary mentor of the year.

He most recently completed his fellowship in Hematology & Medical Oncology at H. Lee Moffitt Cancer Center & Research Institute in Tampa. During fellowship, Dr. Franke grew his passion for learning, teaching and the importance of adapting a multidisciplinary approach to patient care and medical education. He served as one of the inaugural founding members and co-directors of Moffitt’s Multidisciplinary Leadership Journal Club.

Here at UF Health, Dr. Franke will focus on thoracic oncology, seeing patients with lung cancer. He serves as the Associate Research Lead for the Thoracic Cancers Disease Site Group at UF Health Cancer Center.

His clinical and research interests focus on Thoracic and Head & Neck malignancies. He aims to conduct industry-sponsored, and investigator initiated clinical trials, as well as participate in large oncology clinical trial cooperative group efforts to expand patient access to promising novel targeted and immunotherapeutic agents for patients with advanced lung cancer.

Dr. Franke is board certified in Internal Medicine and Medical Oncology and Hematology. He is a member of the International Association for the Study of Lung Cancer (IASLC), American Association for Cancer Research (AACR), American Society of Hematology (ASH), American Society of Clinical Oncology (ASCO), and Florida Society of Clinical Oncology (FLASCO).

He also earned the rank of Eagle Scout with Scouts BSA


Exemplary mentor of the year – Senior resident teaching award
2018 · University of Florida
Dean of Clinical Medicine Excellence Award
2015 · University of Florida
2012 · Alpha Omega Phi Honor Society
Eagle Scout
2006 · Scouts BSA

Board Certifications

  • Internal Medicine
    American Board of Internal Medicine
  • Medical Oncology & Hematology
    American Board of Internal Medicine

Clinical Profile

  • Cancer
Areas of Interest
  • Head and Neck Cancer
  • Lung cancer
  • Lung cancer – small cell
  • Metastasis
  • Non-small cell lung cancer

Research Profile

Open Researcher and Contributor ID (ORCID)


Areas of Interest
  • Clinical Trials Design & Analysis
  • Cancer Immunotherapy
  • Cancer survivorship
  • Chemoresistance
  • Circulating tumor DNA
  • Clinical and translational science
  • Immuno-Oncology
  • Lung cancer
  • Oligometastatic NSCLC
  • Small cell lung carcinoma
  • Small molecule drug discovery
  • Small molecule therapy
  • Smoking Cessation
  • Targeted Cancer Therapy
  • Thoracic Cancers
  • metastatic lung cancer
  • tobacco cessation


A Comprehensive Review of Randomized Clinical Trials Shaping the Landscape of Rectal Cancer Therapy
Clinical Colorectal Cancer. 20(1):1-19 [DOI] 10.1016/j.clcc.2020.07.009.
A Multi-Center Retrospective Analysis Examining the Effect of Dipeptidyl Peptidase-4 Inhibitors on Progression-Free Survival in Patients With Prostate Cancer.
Cureus. 13(4) [DOI] 10.7759/cureus.14712. [PMID] 34055551.
Reduction of immunosuppression for post-transplant lymphoproliferative disorder (PTLD): a single-center experience of allograft survival outcomes
Leukemia & Lymphoma. 62(5):1123-1128 [DOI] 10.1080/10428194.2020.1861266.
Comprehensive literature review of randomized clinical trials examining novel treatment advances in patients with colon cancer.
Journal of gastrointestinal oncology. 11(4):790-802 [DOI] 10.21037/jgo-20-184. [PMID] 32953161.
Post Transplant Lymphoproliferative Disorder risk factors in children: Analysis of a 23-year single-institutional experience.
Pediatric transplantation. 24(5) [DOI] 10.1111/petr.13747. [PMID] 32497335.
Single-institution Retrospective Analysis of Prognostic Factors Influencing Very Late-onset Post-transplant Lymphoproliferative Disorder.
Cureus. 12(2) [DOI] 10.7759/cureus.6912. [PMID] 32190467.
Immunotherapy for Colorectal Cancer: A Review of Current and Novel Therapeutic Approaches
JNCI: Journal of the National Cancer Institute. 111(11):1131-1141 [DOI] 10.1093/jnci/djz093. [PMID] 31322663.
Investigation of Complications Following Port Insertion in a Cancer Patient Population: A Retrospective Analysis.
Clinical Medicine Insights. Oncology. 13 [DOI] 10.1177/1179554919844770. [PMID] 31040735.
National Cancer Institute (NCI) state of the science: Targeted radiosensitizers in colorectal cancer
Cancer. [DOI] 10.1002/cncr.32150. [PMID] 31017664.
Pericardial effusion as an atypical initial presentation of extra-gonadal nonseminomatous germ cell tumor: a case report and literature review.
Oxford medical case reports. 2018(2) [DOI] 10.1093/omcr/omx097. [PMID] 29492268.
Role of bevacizumab for treatment-refractory meningiomas: A systematic analysis and literature review.
Surgical neurology international. 9 [DOI] 10.4103/sni.sni_264_17. [PMID] 30090665.
Total Neoadjuvant Therapy: A Shifting Paradigm in Locally Advanced Rectal Cancer Management.
Clinical colorectal cancer. 17(1):1-12 [DOI] 10.1016/j.clcc.2017.06.008. [PMID] 28803718.
Management of Malignant Bowel Obstruction Associated With GI Cancers.
Journal of oncology practice. 13(7):426-434 [DOI] 10.1200/JOP.2017.022210. [PMID] 28697317.
Post-transplant lymphoproliferative disorder (PTLD): single institutional experience of 141 patients.
Experimental hematology & oncology. 6 [DOI] 10.1186/s40164-017-0087-0. [PMID] 29021921.
The role of radiation therapy in pancreatic ductal adenocarcinoma in the neoadjuvant and adjuvant settings.
Seminars in oncology. 42(1):144-62 [DOI] 10.1053/j.seminoncol.2014.12.013. [PMID] 25726059.


Fellowship – Hematology-Oncology
2018-2021 · H. Lee Moffitt Cancer Center & Research Institute
Residency – Internal Medicine
2016-2018 · University of Florida
Internship – Internal Medicine
2015-2016 · University of Florida
Medical Degree
2011-2015 · Saba University of Medicine
Bachelor of Science in Psychology
2006-2010 · Florida State University

Contact Details

(352) 273-7832
Human Resources Generalist I:
Business Mailing:
PO Box 100278
Business Street:
PO Box 100215